Recently, "urban ornithology" has become one of the priority and independent areas of modern science. In the second half of the 20th century, a lot of work was done in large cities of Europe, and ornithological research in the cities of Central Asia was insufficiently carried out, and this applies to the avifauna of cities in Uzbekistan. The purpose of this study is to determine the current state and patterns of formation of the avifauna of the cities of the Kyzylkum region. The solution of the following tasks was envisaged: Identification of environmental factors that determine the features of the habitat of birds in cities and the patterns of formation and dynamics of urban avifauna; study of the species composition and nature of the stay of birds; to analyze the fauna and bird population of the cities of the Kyzylkum region; to study long-term and seasonal dynamics of the number of birds; assess the adaptation of birds to urban conditions; to reveal the ways of avifauna formation in the cities of the region; determine the relationship of birds to urbanized areas and natural landscapes in different phenological periods; determine the importance of birds in urban environments; to develop a scientific basis for the protection and control of numbers.