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HISTOMORPOLOGY OF PAPILLARY THYROID CARCINOMA AND FOLLICULAR THYROID CARCINOMA IN THE LABORATORY OF ANATOMIC PATHOLOGY UNIT RSUP H.ADAM MALIK MEDAN 2015-2019

Volume: 66  ,  Issue: 1 , December    Published Date: 28 December 2020
Publisher Name: IJRP
Views: 49  ,  Download: 22
DOI: 10.47119/IJRP1006611220201608

Authors

# Author Name
1 Roy Herbon Sinambela 
2 Lidya Imelda Laksmi
3 Delyuzar
4 T.Ibnu Alferraly
5 Joko S Lukito

Abstract

Background: Thyroid carcinoma is a malignancy of the thyroid gland originating from follicular cells or thyroid parafolicles. Consists of Papillary thyroid carcinoma (PTC) and Follicular thyroid carcinoma (FTC). The incidence of thyroid cancer is greatly influenced by age, sex, geography, and other factors. Methods: This study was a descriptive study with a cross-sectional approach. There were 104 samples of thyroid carcinoma diagnosed histopathologically as PTC and FTC from paraffin block at RSUP H. Adam Malik Medan in 2015-2019. Data regarding age, sex, clinical stage were obtained from medical records. Slaid reviews were performed and lymphovascular invasion (LVI), tumor-infiltrating lymphocytes (TILs), and histopathologic subtypes were determined. Results: From 104 samples, PTC and FTC were found mostly in the 45-59 years age group where 32 samples of PTC and 20 samples of FTC. Mostly found in the female sex, where the PTC 61 samples and 21 samples of FTC. The most clinical stage was found at stage I where PTC T3 was 66 samples, N0 65 samples, M0 80 samples while FTC T3 18 samples, N0 23 samples, M0 24 samples. In a total of 57 samples of PTC, LVI was negative, while 21 samples were FTC, LVI was positive. TILs in PTC were found to have a minimum number of 53 samples and FTC with the highest number of 14 samples. The most subtypes are classic PTC with 54 samples and FTC widely invasive in 19 samples.

Keywords

  • water quality standards
  • under graduate education
  • Physico-chemical analysis