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RESISTANCE AND SUSCEPTIBILITY PATTERNS OF S. aureus TO VANCOMICIN AND LINEZOLID

Volume: 36  ,  Issue: 1 , September    Published Date: 27 September 2019
Publisher Name: IJRP
Views: 705  ,  Download: 483

Authors

# Author Name
1 Tuvei Susan Mamusavu

Abstract

Background: Given the rising complication for treating S.aureus infections, information regarding the medical impact of antimicrobial agents remains vital for decision making. Scientific studies investigating patterns of susceptibility of S.aureus to first line drugs such as vancomycin and linezolid have divergent views given that some scientists established S.aureus to be more susceptible to vancomicin while others established S.aureus to be more susceptible to linezolid. This makes it impossible to single out the most effective antibiotic between vancomicin and linezolid. Aim: To investigate the resistance and susceptibility pattern of S.aureus to vancomicin and linezolid. Method: Pus samples from diabetic patients with foot ulcers (DPFUs) were collected for S. aureus screening and susceptibility test. Results: S. aureus isolated from DPFUs at Vihiga County Referral Hospital, Kenya had a susceptibility rate of 36% and 60% to vancomycin and linezolid respectively. Recommendations: Linezolid having the highest susceptibility rate should be used as the first line antibiotic for treating bacterial infections which appear to be resistant to most of the commonly used antibiotics.

Keywords

  • Susceptibilty
  • S.aureus
  • vancomicin