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Understanding Acid-Base Homeostasis in Pediatric Sepsis: A Literature Review

Volume: 140  ,  Issue: 1 , January    Published Date: 03 January 2024
Publisher Name: IJRP
Views: 173  ,  Download: 96 , Pages: 104 - 109    
DOI: 10.47119/IJRP1001401120245959

Authors

# Author Name
1 Wulanda Izmi Riadinata
2 Arina Setyaningtyas
3 Lucky Andriyanto
4 Neurinda Permata Kusumastuti

Abstract

Sepsis kills 5 million people worldwide. Sepsis is prone to acid-base imbalances. This study aimed to determine the effect of sepsis towards acid and base homeostasis. A literature review was used to conduct this investigation. We performed a literature search using the databases PubMed and Google Scholar. 1382 publications were identified in the search results, and 5 studies were relevant and matched the requirements for this investigation. Sepsis patients typically develop acidosis due to type II respiratory failure, renal failure, lactic acidosis, and ketoacidosis. pH is impacted by respiratory and metabolic factors. Hence, it may misrepresent acid-base.

Keywords

  • acid
  • base
  • pH imbalance
  • sepsis