Background: Carpal tunnel syndrome (CTS) is a syndrome that occurs in the medial nerve where there is pressure on the nerve as it passes through the wrist. This syndrome has symptoms of pain in the hands, a feeling of numbness, and tingling in the area innervated by the medial nerve. The prevalence of CTS is more dominated by women than men, where in the UK General Practice Research Database in the year 2000, there were 193 incidents per 100,000 women and 88 incidents per 100,000 men. This meta-analysis was created with the aim of further evaluating the comparison of the degree of pain in CTS between men and women both from an anatomical perspective and from various other aspects so that it can become a study that can be used as a reference in the treatment and prevention of CTS. Objective:  Analyzing the comparison between pain level between men and women Methods: Systematic review and meta-analysis were carried out using the SCOPUS, Web of Science, Science Direct, SAGE, and PUBMED databases. The research results would be screened according to the inclusion criteria. Meta-analysis would be carried out using the fixed effect method to compare the standardised mean differences between pain levels in men and women. Results: The results obtained were 3464 articles, of which there were 7 articles that met eligibility. The pain scale in CTS was measured using the Boston Carpal  Tunnel Questionnaire, PainDETECT, LANSS, and NRS. There was a significant difference between the standardised mean pain levels between men and women, where women have a higher pain level than men. I2 = 0% dan Tau2 = 0.0029 (p<0.0001) (SMD -0.32 95% CI [-0.45 – -0.19]). Conclusions: Female patients were found to experience a higher degree of pain compared to men.

carpal tunnel syndrome

sex

pain