Music has been known for ages to have a strong influence on humans. It has been reported to enhance memory, increase endurance, brighten the mood, and reduce anxiety and depression. Therefore, this study was designed to investigate the effect of calm music and emotional songs on blood pressure and heart rate in healthy female subjects. 30 female subjects were randomly divided into three groups: the control group, the calm music group, and the emotional song group, with each group having 10 subjects. All the subjects were comfortably seated in a restricted room devoid of external noise. Prior to the experiment, the subjects were allowed to rest for 15 minutes. The control group sat down without listening to any music for the duration of the study. The calm music and emotional song groups listened to calm music and emotional song, respectively, for 60 minutes. A digital sphygmomanometer was used for measuring the blood pressure and heart rate at 15 minutes, 30 minutes, 45 minutes, and 60 minutes. The study recorded a significant decrease in systolic blood pressure, diastolic blood pressure, and mean arterial pressure in the test groups compared to the control group, but there was no significant change in heart rate. In conclusion, listening to calm music and emotional songs has the potential to reduce blood pressure in healthy female individuals.