Introduction: Human immunodeficiency virus (HIV) is an infection that attacks the bodys immune system. The progressive immunodeficiency caused by the decrease of CD4+, is responsible for the installation of Advanced HIV disease (AHD). Anemia is the most common hematological complications in HIV patients, that has impact on quality of life, morbidity, and mortality.  Case Report: A 37-year male patient was admitted in hospital with major complains of weakness and general malaise since 5 month before admission. The patient had history of multisexual partner. Physical examination showed the general appearance look moderate ill, both conjunctiva was pale, gingivitis, gum bleeding, oral plaque, and papular eruption on upper and lower extremity. Laboratory test was showed markedly severe anaemia with haemoglobin count of 5.4 g/dL. Anti-HIV rapid test was reactive. CD4+ count showed 10 cell/mm3. We assess the patient with Severe Anaemia, Stage 4 HIV infection pre highly active antiretroviral therapy, Wasting Syndrome, Pancytopenia caused by viral infection, Pruritic Papular Eruption, and Oral Candidiasis. The patient was treated by 4 bag packed red cell transfusion, Fluconazole 150 mg, and Cotrimoxazole 960 mg once daily.  Conculsion: Anemia is the most common hematological complications in HIV patients. Anemia may be encountered as the initial presentation of asymptomatic HIV infection, physicians should be alert to the possibility of HIV infection in every case of anemia. Early diagnosis and treatment of HIV also can help managed the anaemia. Management of anemia in HIV patients depends on the underlying cause.

AIDS

Advanced HIV Disease

anemia in HIV