This study directs attention to an evaluation of how western culture, in the  era of globalization has abraded the indigenous culture of the Ejagham people of Nigeria and Cameroon in the proximate localities of Agbokim (Nigeria) and Nsanarangati (Cameroon). The paper makes pain to explain the extent of homogeneity of heterogeneity in cultural traits among the people in all its ramifications. The specific objective is to examine the overall extent of erosion of the native cultural values by the western exogenous culture, understanding the disparity in response to exogenous culture on the basis of sex and age, and finally to appreciate how appropriately or otherwise some or all patterns of behavioural changes are in conformity with the alien culture. The problem statement is the direction of the objectives based on the need to evaluate the full view essence of the cultural anomie.  Several justifications for the study were equally well brought out. The methodology encapsulates the description of the study area, the universe or population of the study, sampling procedure, method or procedure for data collection and data analysis technique. The results of the statistical analysis in the direction of the hypothesis showed that the null hypothesis was rejected while alternative hypothesis was accepted indicating that there is significant impact of colonization on the native culture of the Ejagham cultural realm in the transboundary area of Agbokim-Nsangarati zone Nigeria Cameroun boundary.