Medical ethics (ME) is an applied branch of ethics which analyzes the practice of clinical medicine and related scientific research based on a set of values that professionals can refer to in the event of any confusion or conflict. ME is particularly relevant in decisions regarding involuntary treatment and involuntary engagement. To practice medical ethics with many challenges from the patients right to autonomy, the patients beneficence and non-maleficence, the patients justice are included. Now, however, evidence-based medicine (EBM) is as important in the developing world as it is in the developed world. Evidence-based practice medicine is one of the ways to reduce health and knowledge gaps significantly. Patient autonomy is done after being explained by the physician based on the EBM. The other three principles also depend on EBM from weak level, average level to strong level. EBM meets the needs, the demands of all four principles of medical ethics. Through this article, the challenges of ME are highlighted below and we introduce ME that can be classified into 4 levels as in the 4 levels of EBM to contribute to an effective balance in the practice of ME.

L-fuzzy soft set

medical ethics; evidence-based medicine; challenge; conflict; effective.