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A Literature Review of Advanced Maternal Age in Pregnant Women with COVID-19

Volume: 116  ,  Issue: 1 , January    Published Date: 02 January 2023
Publisher Name: IJRP
Views: 231  ,  Download: 191 , Pages: 32 - 42    
DOI: 10.47119/IJRP1001161120234385

Authors

# Author Name
1 Sabrina Kemala Hapsari
2 Fairuz Nadhira Hermadiputri
3 Ashon Saadi

Abstract

Background: During pregnancy, the risk of severe manifestation of COVID-19 with a worse maternal outcome can become higher because of the alteration in the immune system and physiological function. In COVID-19 infection, several studies also stated the increased risk of severe disease in advanced maternal age (AMA). Considering that the death and severe case rates in advanced-aged pregnant women with COVID-19 were high, special attention should be focused on this matter. There was still little study that focused on the outcome of COVID-19 in pregnant women with advanced age as well. Therefore, this study aims to evaluate the risks and the outcomes of advanced maternal age-pregnancy with COVID-19. Method: The method used in this paper is the Literature Review which aspires to analyze the risk and the outcome of COVID-19 in advanced maternal-age pregnancy. The databases used in the source search are PubMed, Google Scholar, JAMA, and AJOG. The keywords for the search were advanced maternal age, COVID-19, and pregnancy. Results: The mortality and morbidity of AMA who had COVID-19 were higher than non-AMA pregnant women. Severe conditions of COVID-19 were increased in AMA patients. They were at risk of having ICU admission and intubation. Advanced-aged mothers were more likely to have comorbidity including obesity. They also had a higher risk of adverse pregnancy outcomes. Conclusion: The adverse maternal aged-pregnant women with COVID-19 had higher risks of having comorbidities, severe conditions of COVID-19, adverse pregnancy outcomes, and mortality. Therefore, early risk identification needs to be done to identify the special management for the patients

Keywords

  • Obesity
  • Pregnancy
  • Advanced Maternal Age
  • Preeclampsia
  • COVID-19