Medicine, Health & Food
Volume: 115 , Issue: 1 , December Published Date: 27 December 2022
Publisher Name: IJRP
Views: 396 , Download: 341 , Pages: 424 - 433
DOI: 10.47119/IJRP10011511220224353
Publisher Name: IJRP
Views: 396 , Download: 341 , Pages: 424 - 433
DOI: 10.47119/IJRP10011511220224353
Authors
# | Author Name |
---|---|
1 | Devi Anggraeni |
2 | Pepy Dwi Endraswari |
3 | Musofa Rusli |
4 | Arthur Pohan Kawilarang |
Abstract
Background: Candiduria can represent a variety of conditions, from sample contamination, kidney and collecting system infections, to life-threatening disseminated candidiasis. The prevalence of candiduria is significantly higher in hospitalized patients and may be associated with an increased mortality rate. Until now, most candiduria research has been done in developed countries, while the prevalence varies widely in different parts of the world. Objective: This study aimed to determine the epidemiology and risk factors for candiduria in hospitalized patients at Dr. Soetomo Hospital Surabaya from January to December 2020. Methods: This study is an observational analytic study with a cross-sectional design using medical record data and a total sample of 301 samples consisting of 185 candiduria patients and 116 non-candiduria patients. Results: Among 185 candiduria patients, most patients were female (67.6%) and dominated by the age group 45–59 years (40.5%). Candida albicans was found most commonly (42.7%). No resistance of the studied Candida species to Amphotericin B was found. The prevalence of candiduria in hospitalized patients was 0.55%. Variables that had a significant relationship with candiduria were diabetes mellitus (p=0.005 PR=1.309 95% CI=1.089–1.575), antibiotic use (p=0.006 PR=1.4 95% CI=1.174–1.670), and the use of an Intraurethral Catheter (IUC) (p=0.008 PR=1.292 95% CI=1.074–1.554). While old age, female gender, and corticosteroid therapy had no association with candiduria. Conclusion: The prevalence of candiduria is 0.55%. Diabetes mellitus, antibiotic use, and the use of an Intraurethral Catheter (IUC) have a significant relationship with candiduria in hospitalized patients.