Coronary artery disease (CAD), caused by atherosclerosis, is the leading cause of mortality worldwide. Acehnese people own unique cultures with many traditional events involving various cuisines and possess daily habits that increase the risk of CAD. Measurement of carotid intima-media thickness (CIMT) using ultrasonography (USG) has been considered a non-invasive, inexpensive, and safe procedure to assess atherosclerosis in patients. The aim of this study was to evaluate the association between CIMT and the severity of stenosis assessed by the Gensini score among Acehnese CAD patients. A cross-sectional study was conducted at Dr. Zainoel Abidin Hospital, Banda Aceh from April to June 2022. CIMT was measured using ultrasonography and the severity of coronary stenosis was determined through the Gensini scoring system. The cut-off value of CIMT was also analyzed using the receiver operating characteristic (ROC) curve. Using SPSS software, the Chi-Square test was employed to evaluate the relationship between the two variables, and a p<0.05 was considered statistically significant. A total of 51 CAD patients were enrolled in the study and most of them were males (84.3%). More than half (58.8%) of the patients had abnormal CMIT (≥0.9 mm) with an overall CIMT mean of 1,02 ± 0,30 mm. Severe stenosis was observed in 41 patients (80.4%) with an average Gensisni score of 62.65±51.10. Chi-Square analysis revealed a significant association between CIMT and the severity of coronary stenosis among Acehnese CAD patients (p=0.039). The cut-off value for CIMT towards the Gensini score was 0.92 mm with a sensitivity of 60.9% and specificity of 80.0%, suggesting that CIMT could accurately predict the severity of stenosis in the CAD patients of the present study.

ethnicity

Carotid intima-media thickness

Gensini score

coronary artery disease

Acehnese

ethnicity