Objective: The purpose of study was to extend information prevention of monkeypox virus infection in Thailand. Background: Although monkeypox has been discovered and spread in particular areas, in 2022, monkeypox virus has immensely expanded to other continents and ultimately the global health crisis has occurred. Therefore, the monkeypox 2022 outbreak may negatively affect social contexts. To extend, there is the predisposition of increasing monkeypox infection cases and Thailand might encounter the monkeypox epidemic circumstance. Thus, this study endeavored to congregate monkeypox prevention may provide an initiative or idea regarding prevention in monkeypox outbreak for Thailand. Result: The research confirmed that there are 2 possible prevention methods to protect against infection including self-prevention and vaccination. 2 vaccines are recommended to use for prevention: JYNNEOS and ACAM2000. However, the conditions of JYNNEOS are that it is only recommended for people aged 18 or older with high risk, and must be vaccinated for 2 doses. Apart from that, ACAM2000, or smallpox vaccine, found no exact supporting evidence of effectiveness at current time. In extent, freeze-dry smallpox vaccines which were frozen for more than 4 decades are qualified to use in Thailand. Conclusions: Our data suggests that the JYNNEOS and ACAM2000 vaccines are able to be used, although the JYNNEOS vaccine may be prioritized first. Nonetheless, self-prevention might play a major role in coping with further monkeypox situations in Thailand.

monkeypox prevention

monkeypox vaccination

2022 monkeypox outbreak

monkeypox

smallpox vaccination