Toothpaste is a gel dentifrice used with a toothbrush as an accessory to clean and maintain the aesthetics and health of teeth. Toothpaste is used to promote oral hygiene. The aim of this study is to evaluate the effect of toothpaste on oral microbial flora (bacteria and fungi). The study included 50 people from Ekpoma, 20 males and 30 females, who were chosen at random from around the province. Swab sticks were utilized to aseptically collect samples from each subject's oral cavity (tongue, teeth, and inner cheek) using sterile swab sticks. The organisms isolated are Bacteria: Streptococcus mutans (25), Staphylococcus aureus (10), Escherichia coli (2), Klebsiella spp (5), and Fungi: Candida albicans (4) and Rhizopus spp (2). Close-Up Deep action (Red hot) and Macleans (Fresh mint) were found to be sensitive to all of the organisms discovered, however Pepsodent - Natural white (Gel), Oral ? B weren't (Pro-Health), Close-Up Herbal and Colgate were sensitive to 3 (3) organisms, while the antibiotics sensitivity of the oral fungal flora indicated Close-Up Deep action (Red hot), Macleans (Fresh mint) and Oral ? B (Pro-Health) showed sensitivity to all the fungal isolates while Pepsodent - Natural white (Gel), Close-Up Herbal and Colgate were sensitive to at least one (1) of the fungal isolate indifference. Analysis of the inhibition of bacteria by the toothpaste studied shows that they are more effective for some bacterial species than others. The microbial quality of toothpaste formulations sold on the open market, on the other hand, has met the drug standard, which prohibits the presence of any index, indicator, or pathogenic organism in the toothpaste. drugs to be consumed by the populace. The results from this study indicate the need for further research into the possible value of toothpaste for reducing oral bacteria flora.

Oral

Teeth

Toothpaste

Fungi

Bacteria