Background: Residents' lives in the world of health are often accompanied by stressful conditions, where this is triggered by the specialist medical education program activities that are being undertaken by the anesthesiologist. The COVID-19 pandemic has resulted in an increase in the condition of anesthesiology residents at various educational centers in Indonesia. Including one that happened in Surabaya, to be precise at the Soetomo Hospital. It is known that the higher the level of stress experienced by a person, this can also increase the level of cortisol in the individual's blood. Therefore, this study was structured to analyze the relationship of saliva cortisol levels with stress level of anesthesiology and intensive care of faculty of medicine Airlangga University in the era of the COVID-19 pandemic. Methods: This study was an analytic observational study through a cross sectional design which was measured by the Depression, Anxiety, and Stress Scale (DASS)-42 and their relationship to salivary cortisol levels. Results: The results showed that salivary cortisol levels of the Anesthesiology and Intensive Care FK UNAIR residents before entering the RIK stagnation cycle versus 2 weeks of running the RIK stagnation cycle with a median value of 0.315 g/dL compared to 0.422 g/dL with (95% CI, 0.143, 0.778) g/dL versus (95% CI, 0.179, 2.802) g/dL with p < 0.05. From the results of the DASS-42 questionnaire obtained 2 subjects (5.7%) mild depression, 1 subject (2.9%) moderate depression, 5 subjects (14.3%) mild anxiety, 1 subject (2.9%) moderate anxiety, 1 subject (2,9). %) severe anxiety, 2 subjects (5.7%) mild stress, 5 subjects (14.3%) moderate stress, 1 subject (2.9%) severe stress. Conclusion: Thus, it can be concluded that the stress level of the anesthesiology resident participants in the COVID-19 Pandemic era was not stressful or normal because almost 80% of the subjects did not experience stress.

cortisol

COVID-19

Stress

Anesthesiology