Cumulative fluid balance (CFB) with positive values mentioned in many studies is associated with mortality risk. In general, positive CFB was found in patients with sepsis, acute kidney injury (AKI), and heart failure. Meanwhile, COVID-19 is one of the causes of the conditions mentioned above. This study is a retrospective observational study using a cross-sectional method. Of the 97 samples obtained, 78 samples met the inclusion criteria. Obtained 69.2% male and 30.7% female. In this study, 45 (57.7%) patients had positive CFB, and 33 (42.3%) patients had negative CFB out of a total of 78 patients. The mortality rate was 32 (41.1%) patients who died from 78 patients in August 2020 s.d. October 2020. The optimal cut-off value for the amount of CFB in 72 hours is 516 ml (sensitivity 59.4%; specificity 71.7%). The result of the significant value of the number of CFB in 72 hours and mortality is (p) = 0.019 then p<0.05, which means there is a relationship between the number of CFBs in 72 hours and mortality in COVID-19 patients in the Ruang Isolasi Khusus (RIK) 1 RSUD Dr. Soetomo Surabaya Period August 2020-October 2020. Positive cumulative fluid balance (>516 ml) predicted to increase mortality of COVID-19 patients in Ruang Isolasi Khusus (RIK) 1 RSUD Dr. Soetomo Surabaya Period August 2020-October 2020

COVID-19

cumulative fluid balance

mortality