Introduction : Parturition Premature Imminens (PPI) or the threat of premature birth is the presence of uterine contractions accompanied by cervical changes in the form of dilatation and effacement before 37 weeks of gestation and can cause premature birth. Premature birth is a problem with a high prevalence in the world and is a challenge for doctors, especially obstetricians, to find out the causes and prevention of premature birth. The main problem with premature birth is the lack of success in its managemen. Discussion : The mechanism of preterm labor is not different from that of term labor, namely uterine contractility, cervical ripening, and membrane rupture. The fundamental difference is that the activation process in term labor is part of the physiological activation, whereas in preterm labor it is pathological. The usual path of delivery can be seen based on anatomy, biochemistry, immunology, endocrinology, and clinical symptoms. Prevention should be done in PPI management, as Performed prenatal care, diet, administration of vitamins, hygiene, Activity (work, coitus) is restricted in patients with a history of preterm labor, Immediate treatment if there is infection or comorbidities, Abdominal surgery and dental procedures are postponed until delivery. Special condition as Patients with multiple pregnancies should be on bed rest from the 28th to the 36th week. Fibromyoma, if there are complaints, can be treated with bed rest and analgesics. Surgery is avoided as much as possible. Placenta previa is treated with complete bed rest and blood transfusions to delay the birth of the baby until it is viable. Incompetent cervix should be sutured in the first part of the second trimester as long as all requirements are met. Elective SC and repeat is only done if it is believed that the baby is old enough. Medicines can be used to stop labor. Conslusion : In general, the management of preterm labor includes the administration of a single dose of corticosteroid in women 24-34 weeks' gestation with a risk of delivery within 7 days. In addition, magnesium sulfate can reduce the severity and risk of cerebral palsy in infants when born before 32 weeks of gestation. First-line tocolytics such as beta adrenergic agonists, calcium channel blockers, NSAIDs can be given for prolongation of pregnancy up to 48 hours (administration of antenatal steroids).

, Disease

Management

Preterm birth