Rehabilitation management of Asthma patient, including breathing retraining that could be using incentive spirometry as biofeedback tool for patient when doing breathing exercise. The purpose of the research is to prove effect of home-based incentive spirometry (flow based) on FEV1, FVC, 6-MWT, asthma control status (ACT) and Quality of life (SGRQ) and spirometry test of asthma patient. This experimental study with Randomized Pre-test and Post-test Controlled Group design conducted at Dr Soetomo General Academic Hospital. A total of 16 asthma patients aged 18-40 years were randomly and evenly divided into two groups. An exercise program using Incentive Spirometry (flow based) was given to the intervention group, whereas the control group doing diaphragmatic breathing exercises. Both workouts were performed at home for four weeks with frequency five times per day, each session has ten repetitions. Results indicates that exercise with home-based incentive spirometry (flow based) showed improvements in FVC parameters (p-value 0.009) large effect size (1.25), 6 MWT distance (p-value 0.005) large effect size (1.40); and activity score SGRQ (p-value 0.041) large effect size (0.8). Giving 4 weeks of home-based exercise with Incentive Spirometry-(flow-based) improves FVC, 6-MWT distance, and activity score of quality of life (SGRQ) in asthmatic patient.