The purpose of the present study is to discover the sedation assessment tool and how to use them, the complications of sedation drugs, and evaluate the appropriate sedation according to the patient's condition, by anesthesiologists in Misurata hospitals. There were a total of 30 anesthesiologists. The respondents were worked in different hospitals in Misurata (public and private hospitals) which include: Misurata Medical Center, Alhekma Hospital, and alzohoor hospital. Questionnaires were distributed to anesthesiologists in 2021. Through our results, we note that the majority of the respondents have ages from 31-35 years old, that most of the anesthesiologists are dominantly male, that greater number of respondents or 64 percent (n=19) were worked in Misurata Medical Center, 13 percent (n=4) were worked in Al-jazera, 10 percent (n=3) were worked in Al-hekma, 7 percent (n=2) were worked in Al-zohuor, Onocylogy and Zraiq at rate of 3 percent (n=1) for each, that most of the respondents have from 1-5 years of working experience in ICU, that the most anesthesiologists were used assessment tools and that the vast majority of anesthesiologists use RASS. While none of them use ATICE, the vast majority of anesthesiologists use Dormicum by 63% in cardiovascular, the most common drug is used Dormicum by 33% in respiratory, the most anesthesiologists use Ketamine by 33% in truma / ortho, the most anesthesiologists use dormicum by 50% in vascular, the most of anesthesiologists use dormicum by 37% in neurology, the most of anesthesiologists use propofol by 35% in gynecology, the most of anesthesiologists use ketamine by 50% in pediatric. Through the current study, we concluded that most of the target audience use the assessment tools in the intensive care unit, which was the most common, which is RASS. Also, the most common sedation drugs used in the intensive care unit are Dormicum, ketamine and propofol, and for each drug there are complications. The results showed that the most common complications (hypotension, respiratory depression.