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RELATIONSHIP BETWEEN CLINICOPATOLOGICAL DATA WITH BASAL CELL CARCINOMA HISTOPATHOLOGY SUBTYPES

Volume: 90  ,  Issue: 1 , December    Published Date: 10 December 2021
Publisher Name: IJRP
Views: 428  ,  Download: 306 , Pages: 393 - 403    
DOI: 10.47119/IJRP1009011220212543

Authors

# Author Name
1 Harry Sundoro
2 T. Ibnu Alferraly
3 Delyuzar
4 Soekimin
5 Joko S Lukito
6 Lidya Imelda Laksmi

Abstract

Background: Basal cell carcinoma (BCC) is an epithelial malignancy most commonly found in human about 75-80% of non-melanoma cancer. At the moment, BCC has been one of the most important health problems, due to increasing number of incidents. Studies about the relationship between clinicopathologic data and histopathologic subtypes of BCC in Indonesia especially in Medan are still limited. Therefore, the researchers are interested in this study. Objective: To analyze the relationship between clinicopathologic data and histopathologic subtypes of BCC. Methods: A cross-sectional study was performed using formalin-fixed tissue paraffin blocks from 38 BCC patients. Clinical data such as age, gender, occupation, ethnic groups, tumour location and size were recorded. Then, each BCC cases were reviewed for determining histopathologic subtypes of BCC. Then, the relationship between clinicopathologic data and histopathologic subtypes in BCC was assassed and analyzed with statistical software by using the chi-square test or fisher exact test. Results and Discussion: About 68.4% samples aged >60 years old; 57.9% women; 36.8% housewives; 44.7% located in mid face, mostly in palpebra; 50% with size of ?1.5cm; 78.9% nodular BCC; and 89.5% with lower recurrence risks. Men tend to have BCC than women because they smoke more and tend to work outdoor. That?s why they are more exposed to UV rays. These factors are thought to trigger tumour growth. Conclussion: There were no statistically significant relationships between age, gender, occupations, ethnic, tumour location and size with histopathologic subtypes of BCC

Keywords

  • BCC
  • Clinicopathology
  • histopathologic subtypes