Brain calcification can occur physiologically and pathologically. Physiological calcification is associated with a degenerative process with globus pallidus as the most common location. Pathological calcifications are associated with several causes such as idiopathic or secondary due to disturbances in mineral metabolism in the body. Fahr disease is a syndrome characterized by calcium and phosphate deposition in several areas, namely the periventricular area, cerebellum and dentate nucleus. Fahr disease is a rare disease with an incidence of <1:100,000 in the general population. In this case report, we describe 2 cases Fahr's disease both in 6th decade of age. Both of these cases present with a clinical manifestation of seizures. The etiology behind the first case is hypoparathyroid post-thyroidectomy while the second case is idiopathic. Imaging showed bilateral calcifications of the basal ganglia and other areas such as the cerebellum and ventricles.

Fahr disease

Intracranial Calcification

Seizures

Parathyroidism