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Procalcitonin Levels in Pregnant Women With or Without Severe Acute Respiratory Syndrome-2 (SARS-CoV-2) Infection

Volume: 82  ,  Issue: 1 , August    Published Date: 12 August 2021
Publisher Name: IJRP
Views: 666  ,  Download: 534 , Pages: 75 - 79    
DOI: 10.47119/IJRP100821820212139

Authors

# Author Name
1 Darmie Tumangger
2 Manggala Pasca Wardhana
3 Hermanto Tri Joewono

Abstract

Background : Coronavirus Disease (Covid-19) can affects all levels of society, there is no exception for pregnant women. Physiological changes and modulate immune response occur during pregnancy as a form of tolerance to fetal-allogenic, as well as reserving the ability to fight against microorganism. Inflammatory response can be shown by circulating biomarkers that can represent inflammatory status like neutrophile, lymphocyte and procalcitonin. There has been a lot of research before, that indicate the biomarkers can be use as predictors to diagnosis and prognosis of Covid-19. Objective : This study aims to determine whether there are differences in NLR, PLR, and procalcitonin of pregnant women and infected by SARS-CoV-2 at third trimester gestasional age Methods : Prospective cross sectional study was conducted between January and March 2021 among 48 pregnant women with or without Covid-19 infection. Results : This study analyze 24 pregnant women with no infection and 24 pregnant women with Covid-19 infection. There were patients with asymptomatic (n=14), mild symptom (n=8) and severe (n=2). Procalcitonin levels in non-infected and infected group were 156,29 (93,72?445,5) and 212,25 (111,8?650,5) respectively. Results : Procalcitonin value tends to be the same in non-infected and infected Covid-19 groups. Even in infected group based on severity disease there was no difference procalcitonin levels.

Keywords

  • Covid-19 in pregnancy
  • procalcitonin
  • inflammatory biomarker