Introduction: Retinopathy of prematurity is a potentially blinding disease of the eye due to abnormal retinal vascularization. Gestational age, preterm birth, oxygen therapy, and RBC transfusion are some of the factors associated with ROP. Purpose: This study aims to determine the relation between gestational age, birth weight, duration of oxygen therapy, and RBC transfusion with ROP. Methods: This research is a case-control study using medical records data from Dr. Soetomo General Hospital in the period of January ? June 2019. Data is analyzed using logistic regression analysis in SPSS v.25. Results: The case group consists of 22 patients with ROP while the control group consists of 66 patients without ROP. Gestational age (p=0.030; OR=3.10, 95% CI 1.113-8.606) and duration of oxygen therapy (p=0.012; OR=3.75, 95% CI 1.342-10.481) shows a statistically significant relation with ROP. There is no relation between birth weight (p=0.098; OR= 2.30, 95% CI 0.857-6.171) and RBC transfusion (p=0.881; OR=1.09; 95% CI 0.343-3.480) with ROP. Conclusions: There is a relation between gestational age and duration of oxygen therapy with ROP. Meanwhile, birth weight and RBC transfusion have no relation with ROP.

retinopathy of prematurity

Low birth weight infants

risk factor

Preterm birth

Duration of oxygen therapy

RBC transfusion