Biology and Life Sciences

Biology and Life Sciences


Pages: 7  ,  Volume: 38  ,  Issue: 1 , October   2019
Received: 11 Oct 2019  ,  Published: 25 October 2019
Views: 174  ,  Download: 9


# Author Name
1 Shaira J. Limpahong
2 Nurhaliza D. Moya
3 Robert A. Sapungan


Bacterial infection are currently life-threatening. From the discovery of Penicillin, series of antibiotics were formulated to kill different pathogenic bacteria due to the constant evolving of bacterial resistance. But then, the use and study of medicinal plants as antibiotic are still in progress, hence this study focused on the antibacterial effect of Allium fistulosum against Pseudomonas aeruginosa. Quantitative experimental research design were used in this study. Antimicrobial Susceptibility Testing were utilized to analyse the minimum inhibitory effect of the Allium fistulosum extract in different concentration against Meropenem and distilled water. It found out that there is no significant difference in the zone of inhibition of Pseudomonas aeruginosa treated with 100%, 75%, and 50% concentration of Allium fistulosum extract and positive control. Hence Allium fistulosum extract is not effective as antibacterial agent against Pseudomonas aeruginosa. The researchers recommend to further study the effectiveness of the plant extract to other pathogenic bacteria.


  • welsh onion
  • pseudomonas aeruginosa
  • meropenem
  • References

    Antibacterial effect of Onion- Mr. Ahmed M. Kabrah1, Dr. Hani S. Faidah2, Dr. Ahmad M Ashshi1, Mrs. Safaa A. Turkistani3, Sch. J. App. Med. Sci., 2016; 4(11D):4128-4133, Retrieved May 08, 2019 from,

    Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies Volume 37, Issue 1, January–February 2019, retrieved April 26, 2019, from

    Assessment of antimicrobial activity of onion extract (Allium cepa) on Streptococcus mutans and Streptococcus sanguinis; in vitro study- Pourshahidi S., Department of Oral medicine, Dental school, Shiraz University of medical Sciences, Shiraz, Iran, Advances in Natural and Applied Sciences, 6(8): 1609-1613, 2012, Retrieved April 15, 2019 from,

    Bioactive polar natural compounds from garlic and onions; Phytochemistry Reviews 11(2-3) June 2012; Retrieved March 30, 2019, from

    Evaluation of antioxidative properties of Allium species growing wild in Italy by Cristina Nencini ,Federica Cavallo, Anna Capasso, Gian Gabriele, Franchi Giorgi, Giorgio Lucia Micheli; 18 May 2007; Retrieved May 02 2019 from

    Herb: Welsh Onion Latin name: Allium fistulosum Family: Alliaceae (Onion Family), Retrieved December 18, 2018, from

    Indian Journal of Hill Farming Welsh Onion (Allium fistulosum L.): A Promising Spicing-Culinary Herb of Mizoram, December 2017, Volume 30, Issue 2, Page 201-208, Retrieved March 30, 2019 from,,

    Isolation and selection of plant growth-promoting bacteria associated with sugarcane; Ariana Alves Rodrigues, Marcus Vinicius Forzani; Apr./Jun. 2016, from

    Medicinal Importance of Allium Species: A current review Shakeel Ahmad Khan, Mehwish Jameel, Sadia Kanwal, Sammia Shahi, Volume 2; Issue 3; May 2017; Page No. 29-39, Retrieved July 28, 2019, from

    Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections; V. Behrends ,B. Ryall ,J. E. A. Zlosnik ,D. P. Speert ,J. G. Bundy; 17 July 2012; Retrieved May 30, 2019, from

    Production and characterization of an interspecific hybrid between leek and garlic; Theor Appl Genet (2003) 107:1–5; Retrieved April 30, 2019, from

    Pseudomonas aeruginosa Pathogenesis and Pathogenic Mechanisms Alaa Alhazmi International Journal of Biology; Vol. 7, No. 2; 2015, Retrieved December 30, 2018, from

    Pseudomonas aeruginosa: A review of their Pathogenesis and Prevalence in Clinical Settings and the Environment; Klrissa Streeter,Mohammad Katouli; Infect Epidemiol Med. 2016 Winter; Volume 2, Issue 1: 25-32; Retrieved June 27, 2019 , from

    Pseudomonas infections: What to know Last reviewed Thu 5 July 2018 By Scott Harris, Retrieved December 31, 2018, from

    Quercetin Influences Quorum Sensing in Food Borne Bacteria: In-Vitro and In-Silico Evidence; Venkadesaperumal Gopu, Chetan Kumar Meena, Prathapkumar Halady Shetty; August 6, 2015, Retrieved March 30, 2019, from

    Response of Japanese Bunching Onion (Allium fistulosum L.) to nitrogen fertilization, Eugeniusz Koáota, Katarzyna Adamczewska-Sowi?ska, Cecylia Ukla?ska-Pusz Wrocáaw University of Environmental and Life Sciences, Retrieved February 15, 2019, from

    The time-related changes of antimicrobial resistance patterns and predominant bacterial profiles of burn wounds and body flora of burned patients; Ulku Altoparlak, Serpil Erol, Mufide N.Akcay, Fehmi Celebi, Ayten Kadanali; Volume 30, Issue 7, November 2004; Retrieved May 25, 2019, from

    Ther Clin Risk Manag(2006) Dec; 2(4): 401–415. Published online 2006 December Meropenem in the treatment of complicated skin and soft tissue infections, Retrieved January 22, 2019, from

    Trend of antibiotics susceptibility of multidrugs resistance Pseudomonas aeruginosa in Jakarta and surrounding areas from 2004 to 2010, Accepted 26 January, 2012, Retrieved July 15, 2019 from,