Medicine, Health & Food

Medicine, Health & Food

Vitamins and their relations to oral health: A review study

Pages: 13  ,  Volume: 22  ,  Issue: 1 , February   2019
Received: 17 Feb 2019  ,  Published: 03 March 2019
Views: 76  ,  Download: 0

Authors

# Author Name
1 Amer A. Taqa
2 Faehaa Azher Al-Mashhadane

Abstract

oral disease, a relevant public health problem, is considered a common disease of many people. In this respect, vitamins may be a modifying factor in the progression and healing of the oral diseases and promoting oral and dental health. Vitamins have been recommended as nutrients for prevention and treatment of some pathological conditions, such as cardiovascular diseases, cancer and obesity. Thus, an approach to determine how the different vitamin types could improve oral and dental health is necessary to further understanding of the potential benefits and risks of vitamins supplementation use. For this review of English-written literature which included researches on the relationship of each vitamin with oral and dental health, was conducted.

Keywords

  • vitamin; gingivitis; oral health; periodontitis; caries.
  • References

    References

    1. Anbarcioglu, E ., Kirtiloglu, T., Ozturk, A ., Kolbakir, F., Ac?kgoz, G., Colak, R. Vitamin D Deficiency in Patients with Aggressive Periodontitis. Oral Dis.31. doi: 10.1111/odi.12968(2018).

    2. Mikhail, FF., El-Din, M., Ibrahim, T., Zekry, K., Nemat, A., Nasry, S. Effect of Laser Therapy on the Osseointegration of Immediately Loaded Dental Implants in Patients under Vitamin C, Omega-3 and Calcium Therapy. Open Access Maced JMedSci.20;6(8):1468-1474 (2018).

    3. Brunild, D., Besiana, E., Lea, K., Eppo, BW., Edwin, MO . Does       dental caries affect dental development in children and adolescents?.  Bosn J Basic Med Sci. 18(2),198-205(2018).

    4.Vanishree, T., Panchmal, GS., Shenoy, RP., Jodalli, P.,  Sonde, L. Caries Prevention: Vitamin Way - A Novel Approach International Journal of Health Sciences & Research. 6; 1:488-484(2016).

    5. Dudding, T., Thomas, SJ., Duncan, K., Lawlor, DA., Timpson, NJ. Re-Examining the Association between Vitamin D and Childhood Caries. PLoS ONE 10(12): e0143769(2015).

    6. Akbari, S.,  and  Rasouli-Ghahroudi, A. Vitamin K and Bone Metabolism: A Review of the Latest Evidence in Preclinical Studies. BioMed Research International (2018).

    7. Makrygiannakis, MA., Kaklamanos, EG., Athanasiou, AE. Effects of systemic medication on root resorption associated with orthodontic tooth movement: a systematic review of animal studies. Eur J Orthod. 9. doi: 10.1093/ejo/cjy048(2018).

    8. Iosub Ciur, MD., Zetu, IN., Haba, D., Viennot, S., Bourgeois, D., Andrian, S. Evaluation of the Influence of Local Administration of Vitamin D on the Rate of Orthodontic Tooth Movement. Rev Med Chir Soc Med Nat Iasi.  120(3):694-99(2016).

    9. Marshall, TA., Levy, SM., Broffitt, B., Warren, JJ., Eichenberger- Gilmore, JM., Burns, TL., Stumbo, PJ. Dental caries and beverage consumption in young children. Pediatrics. 112(3 Pt 1):e184-e191(2003).

    10. Varela-López,  AI.,  Navarro-Hortal,  MD., Giampieri,  FD.,  Bullón,  PID. , Battino MID and  Quiles JL. Nutraceuticals in Periodontal Health: A Systematic Review on the Role of Vitamins in Periodontal Health Maintenance.Molecules.23, 1226;doi:10.3390/molecules23051226(2018).

    11. Pino-Lagos,k., Micah, JB.,  and Randolph, JN. Retinoic Acid in the Immune System.Ann N Y Acad Sci.1143: 10.1196/annals.1443.017. doi:  10.1196/annals.1443.017(2008).

    12. Varela-López, A; Giampieri, F; Bullón, P; Battino, M; Quiles, JL. A systematic review on the implication of minerals in the onset, severity and treatment of periodontal disease. Molecules., 21,1183(2016).

    13. Kutner,  A and  Brown, G. Vitamins D: Relationship between Structure and Biological Activity. Int. J. Mol. Sci. 19, 2119; doi:10.3390/ijms19072119(2018).

    14. Burton, GW., Ingold, KU. beta-Carotene: an unusual type of lipid antioxidant. Science. 11;224(4649):569-73(1984).

    15. Greer, JB., Greer, P., Sandhu, BS., Alkaade, S., Wilcox, CM., Anderson, MA., Sherman, S., Gardner, TB., Lewis, MD., Guda, NM., Muniraj, TConwell DCote GAForsmark CEBanks PATang GStello KGelrud A., Brand, RE., Slivka, A., Whitcomb, DC., Yadav, D. Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients. Nutr Clin Pract.   13. doi: 10.1002/ncp.10186(2018).

    16. Sobaniec, H., Sobaniec, W., Sendrowski, K., Sobaniec, S., Pietruska, M. Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy. Adv Med Sci. 52 Suppl 1:204-6(2007).

    17. Khmelevski?, IV., Danilevski?, NF., Borisenko, AV., Poberezkina, NV. Effect of vitamins A, E and K on the indices of the glutathione antiperoxide system in gingival tissues in periodontosis. Vopr Pitan.4:54-6(1985).

    18. Rathee, M.,  Bhoria, M., Kundu, R. Vitamin A and Oral Health: A Review Medical Science.3 : 10(2013).

    19. Kulkarni, V., Bhatavadekar, NB., Uttamani, JR. The effect of nutrition on periodontal disease: a systematic review. J Calif Dent Assoc.42(5):302-11(2014).

    20. Hamasaki, T., Kitamura, M., Kawashita, Y., Ando, Y., Saito, T. Periodontal disease and percentage of calories from fat using national data. J. Periodontal Res.52,114–121(2017).

    21.Weingärtner, J., Lotz, K., Fanghänel, J., Gedrange, T., Bienengräber, V., Proff, P. Induction and prevention of cleft lip, alveolus and palate and neural tube defects with special consideration of B vitamins and the methylation cycle. J Orofac Orthop.68(4):266-77(2007).

    22. Wang, H., Li, L., Qin, LL., Song, Y., Vidal-Alaball, J., Liu, TH. Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. Cochrane Database Syst Rev.15;3:CD004655. doi: 10(2018).

    23. Ishimiya, M., Nakamura, H., Kobayashi, Y., Noguchi-Shinohara, M., Abe, C., Dohmoto, C., Ikeda, Y., Tokuno, K., Ooi, K., Yokokawa, M., Iwasa, K., Komai, K., Kawashiri, S., Yamada, M. Tooth loss-related dietary patterns and cognitive impairment in an elderly Japanese population: The Nakajima study. PLoS One.15;13(3):e0194504. doi: 10.1371/journal.pone(2018).

    24. Hugar, SM., Dhariwal, NS., Majeed, A., Badakar, C., Gokhale, N., Mistry, L. Assessment of Vitamin B12 and Its Correlation with Dental Caries and Gingival Diseases in 10- to 14-year-old Children: A Cross-sectional Study. Int J Clin Pediatr Dent.10(2):142-146(2017).

    25.Grant, WB. Vitamin D and health in the Mediterranean countries.      Hormones (Athens).12. doi: 10.1007/s42000-018-0059-8(2018).

    26. Pontes, HA., Neto, NC., Ferreira, KB., Fonseca, FP., Vallinoto, GM., Pontes, FS., Pinto, DS. Oral manifestations of vitamin B12 deficiency: a case report. J Can Den Assoc.75(7):533-537(2009).

    27. Do?an, A., Tunca, Y., Ozdemir, A., Sengül, A., Imirzalio?lu, N. The effects of folic acid application on IL-1beta levels of human gingival fibroblasts stimulated by phenytoin and TNFalpha in vitro: a preliminary study. J Oral Sci.43(4):255-60(2001).

    28. Al-Mashhadane, FA., Al-Mashhadane, AA., Taqa, AA. Folic Acid Supplementation: A Review of the:51-59(2018).

    29. Jaeri, Lee and Jung-Chul, P., et al. Improvement of periodontal healing after periodontal surgery supported by nutritional supplement drinks. J Periodontal implant. Sci.44:109-117(2014).

    30. Neiva, RF., Al-Shammari, K., Nociti, FH., Soehren, S., Wang, HL. Effects of vitamin-B complex supplementation on periodontal wound healing. J Periodontol.76(7):1084-91(2005).

    31. Maxfield, L & Jonathan, SC. Vitamin, C, Deficiency (Scurvy). StatPearls Publishing LLC.http://creativecommons.org/licenses/by/4.0/ (2018).

    32. Fridell1, S., Ström, E.,  Agebratt, C.,  Leanderson, P.,  Guldbrand, H &  Nystrom, FH. A randomised study in young subjects of the effects of eating extra fruit or nuts on periodontal inflammation. BDJOPEN.3,17022; doi:10.1038/bdjopen(2018).

    33. Li, X., Tang, L., Lin, YF., Xie, GF. Role of vitamin C in wound healing after dental implant surgery in patients treated with bone grafts and patients with chronic periodontitis. Clin Implant Dent Relat Res.  24. doi: 10.1111/cid.12647(2018).

    34. Lee, JH., Shin, MS., Kim, EJ., Ahn, YB., Kim, HD. The association of dietary vitamin C intake with periodontitis among Korean adults: Results from KNHANES ?. PLoS One.  10;12(5):e0177074. doi: 10.1371/journal(2017).

    35. Mithra, NH., Kumari, S., Hegde, ND & Shilpa, SS. Relation between salivary and serum vitaminC levels and  dental caries experience in adults- a biochemical study. NUJHS. 3,4, ISSN 2249-7110(2013).

    36. Li, X., Tang, L., Lin, YF., Xie, GF. Role of vitamin C in wound healing after dental implant surgery in patients treated with bone grafts and patients with chronic periodontitis. Clin Implant Dent Relat Res. 24. doi: 10.1111/cid.12647(2018).

    37.Al-Mashhadane, AM.,  Taqa, GAA., Al-Sandook, TA. Effects of meloxicam on serum level of bone alkaline phosphatase,osteocalcin and bone density in a sheep model. International Journal of Enhanced Research in S cience Technology & Engineering. 3,1: 57-63 (2014).

    38.  Chhonkar, A., Gupta, A., Arya, V. Comparison of Vitamin D Level of Children with Severe Early Childhood Caries and Children with No Caries. Int J Clin Pediatr Dent. 11(3):199-204(2018).

    39. Anbarcioglu, E., Kirtiloglu, T., Ozturk, A., Kolbakir, F., Ac?kgoz, G., Colak, R. Vitamin D Deficiency in Patients with Aggressive Periodontitis. Oral Dis. 31. doi: 10.1111/odi.12968(2018).

    40. Peri?, M., Cavalier, E. , Toma, S., Lasserre, JF. Serum vitamin D levels and chronic periodontitis in adult, Caucasian population-a systematic review. J Periodontal Res. 53(5):645-656. doi: 10.1111/jre.12560(2018).

    41. Chhonkar, A., Gupta, A., Arya, V. Comparison of Vitamin D Level of Children with Severe Early Childhood Caries and Children with No Caries. Int J Clin Pediatr Dent.11(3):199-204(2018).

    42. Kühnisch, J., Thiering, E., Heinrich-Weltzien, R., Hellwig, E., Hicke, R., Heinrich, J. Fluoride/vitamin D tablet supplementation in infants-effects on dental health after 10 years. Clin Oral Investig.  21(7):2283-2290. doi: 10.1007/s00784-016-2021-y(2017).

    43.Woelber1, JP., Bremer, K., Vach, K., König, D., Hellwig, E., Ratka-Krüger, P.,  Al-Ahmad, A and  Tennert, C. An oral health optimized diet can reduce gingival and periodontal inflammation in humans - a randomized controlled pilot study. Woelber et al. BMC Oral Health.17:28 DOI 10.1186/s12903-016-0257-1(2017).

    44. Luo, PP., Xu, HS., Chen, YW., Wu, SP. Periodontal disease severity is associated with micronutrient intake. Aust Dent J. 63(2):193-201. doi: 10.1111/adj.12606. Epub. 23(2018).

    45. Bashutski, JD., Eber, RM., Kinney, JS., Benavides, E., Maitra, S., Braun, TM., Giannobile, WV., and McCauley, LK. The Impact of Vitamin D Status on Periodontal Surgery Outcomes J Dent Res 90(8):1007-1012(2011).

    46. Iqubal1, A., Khan, M., Kumar, P., Kumar, A., Ajai, K. Role of Vitamin E in Prevention of Oral Cancer:A Review Journal of Clinical and Diagnostic Research. 8(10): ZE05-ZE07(2014).

    47. Chaitanya, NC., Muthukrishnan, A., Babu, DB., Sanjeeva Kumari, C.,  Lakshmi, MA.,  Palat, G.,  and Alam, KS. Role of Vitamin E and Vitamin A in Oral Mucositis Induced by Cancer Chemo/Radiotherapy- A Meta-analysis. J Clin Diagn Res.11(5): ZE06–ZE09(2017).

    48. Wójci, D.,  Krzewska, A., Szalewski, L., Pietryka-Micha?owska, E., Szalewska,  M.,  Krzewski, S.,  Pels, E., Be_n-Skowronek, L. Dental caries and vitamin D3 in children with growth hormone deficiency. Medicine 97:8(2018).

    49. Zehnder, JL. Drugs Used in Disorders of Coagulation IN: Basic & Clinical Pharmacology.McGraw-Hill Education, Fourteenth Edition:p608-621(2018).

    50.Akbari, S and Rasouli-Ghahroudi, AA. Vitamin K and Bone Metabolism: A Review of the Latest Evidence in Preclinical Studies BioMed Research International Volume, Article ID 4629383: 8. https://doi.org/10.1155/2018/4629383(2018).

    51. Rasouli-Ghahroudi, AA., Akbari, S., Najafi-Alishah, M and Bohloli, M. The Effect of Vitamin K2 on Osteogenic Differentiation of Dental Pulp Stem Cells: An In Vitro Study. Regeneration, Reconstruction & Restoration. 2(1):26-29(2017).

    52. Southward, KA. hypothetical role for vitamin K2 in the endocrine and exocrine aspects of dental caries. Medical Hypotheses. 84: 276–280(2015).