Biology and Life Sciences

Biology and Life Sciences

Evaluation of Antimicrobial and Antioxidant Properties of Myanmar Herbal Plants

Pages: 12  ,  Volume: 5  ,  Issue: 2 , May   2018
Received: 01 Jun 2018  ,  Published: 03 June 2018
Views: 188  ,  Download: 119


# Author Name
1 Su Win Aye


In this article potential antimicrobial and antioxidant activities of the selected herbal extracts obtained from twelve plants from their different parts (leaf, stem, bark, seed and fruit) that have been traditionally used as general health supplements in Myanmar. The aim of this current research was to evaluatate the antimicrobial and antioxidant potential of ethnolic crude extracts of all these plants, as well as their total phenol contents. In vitro antimicrobial activity was evaluated against six strains; Escherichia coli, Bacillus cereus, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Enterococcus faecalis. by agar well diffusion method. Among all of these plant extracts, the extract of Cassia fistula was strongly inhibited against Enterococcus faecalis. The most antioxidant activities against DPPH were displayed by the extract of Celastras paniculata Wild. and Piper nigrum exhibiting 88.38% and 85.43% inhibition respectively. And the highest value of reducing power was observed by the extract of Celastras paniculata Wild.. and followed by Cassia fistula. Similarity, the highest amount of total phenolic contents was found in Cassia fistula. The brine shrimp lethality assay was also obsoleted to examine the toxic potential of plant extracts. Based on the above results, it can be concluded that the plant extract of Cassia fistula have greatest potential as a source of natural antioxidant and antimicrobial agents than other plant extracts. In the future, plant-derived bioactive compounds will be an essential aspect of the therapeutic agents to accelerate their future discovery in biomedical and natural product research.


  • antimicribial; antioxidant
  • brine shrimp lethality
  • Cassia fistula
  • References

    [1]  Kameshwara Rao C, 2000, Database of Medicinal Plants, Government of Karnataka, India, p. 1–23.

    [2] Subramani SP, Goraya GS, 2003, Some Folklore Medicinal Plants of Kolli hills, Record of a Watti vaidyas Sammelan, J Econ Taxon Bot.

    [3] Zhao, J., Shan, T., Mou, Y., and Zhou, L., 2011, Plant-derived Bioactive Compounds Produced by Endophytic Fungi, Mini Rev. Med Chem, 11, p.159–168.

    [4] H.C. Voon, R. Bhat, R. Gulam, 2012. Flower Extracts and their Essential Oils Aspotential Antimicrobial Agents,  Comprehensive Reviews in Food Science and Food Safety 11, p. 34–55.

    [5] Shahidi F, Naczk M, , 2003. Phenolics in Food and Neutraceuticals, Boca Raton: CRC Press.

    [6] Ghimire BK, Seong ES, Kim EH, et al., 2011. Comparative Evaluation of the Antioxidant Activity of Some Medicinal Plants Popularly used in Nepal. J Med Plant Res; 5(10): p. 1884-1891.

    [7] Mates JM, Segura JA, Alonso FJ, Marquez J,  2009. Natural Antioxidants: Therapeutic Prospects for Cancer and Neurological Diseases,  Mini Rev Med Chem, 9(10), p. 1202-1214.

    [8] Kim H, 2005. Neuroprotective Herbs for Stroke Therapy in Traditional Eastern Medicine, Neurol Res; 27(3), p. 287-301.

    [9] Halliwell, B., Gutteridge, J.M.C., 1999. Free Radicals in Biology and Medicine, Oxford University Press, United Kingdom.

    [10] Rakesh, S.U., Priyanka, R.P., Sagar, R.M., 2010. Use of Natural Antioxidants to Scavenge Free Radicals: a major cause of diseases, Int. J. PharmTech., Res. 2(2), p. 1074–1081.

    [11] George M, Joseph L, Ramaswamy, 2009. Anti-allergic, Anti-pruritic, and Anti-inflammatory Activities of Centella asiatica extracts,  Afr J Tradit Complement Altern Med, 6(4), p. 554-559.

    [12] Teng Wah Sam, 1993. Bioactive Natural Products, CRC press, Inc. Penang, p. 442-456.

    [13] Parra, L.A., Yhebra, R.S., Sardiñas, I.G., Buela, L.I., 2001. Comparative Study of the Assay of Artemia salina L. and the Estimate of the Medium Lethal Dose (LD50 value) in Mice, to Determine Oral Acute Toxicity of Plant Extracts,  Phytomed, 8,p. 395-400.

    [14] Villano, D., Fernandez-Pachon, M.S., Moya, M.L., Troncoso, A.M., Garc?a-Parrilla, M.C., 2007. Radical Scavenging Ability of Polyphenolic Compounds towards DPPH Free Radical, Talanta 71, p. 230–235.

       [15] Zhao, H., Fan, W., Dong, J., Lu, J., Chen, J., et al, 2008. Evaluation of Antioxidant Activities and Total Phenolic Contents of Typical Malting Barley Varieties, Food Chem. 107, p. 296–304.

    [16] Singleton, V. L. & Rossi, J. A. 1999. Colorimetry of Total Phenolics with Phosphor-molybdic-phosphotungstic Acid Reagents, American Journal of Enology and Viticulture 16, p. 144-158.