Medicine, Health & Food

Medicine, Health & Food

Archive
Join as an Editor/Reviewer

Brain Infarction Volume Through Non-Contrast Head MSCT Scan In Various Plasma Fibrinogen Level

Volume: 59  ,  Issue: 1 , August    Published Date: 10 September 2020
Publisher Name: IJRP
Views: 46  ,  Download: 23
DOI: 10.47119/IJRP100591820201394

Authors

# Author Name
1 Rizcka Febriasari
2 Widiana Ferriastuti
3 Bambang Soeprijanto

Abstract

Ischemic stroke occurs due to a blockage of blood vessel flow caused by thrombus. One of elements that plays a crucial role in thrombus formation is fibrinogen. Multiple Slice Computed tomography (MSCT) scan is the main modality in diagnosing stroke. This study aims to evaluate brain infarction volume through non-contrast head MSCT Scan in various plasma fibrinogen level of acute ischemic stroke patient. This was a descriptive study with retrospective design conducted from July 2019 to February 2020 at Dr. Soetomo General Hospital, Surabaya, Indonesia. Sample of this study was ischemic stroke patients who met inclusion criteria. Data regarding plasma fibrinogen level was obtained through medical records. Brain infarction volume was measured using non-contrast head MSCT scan. There were 84 samples in this study. Infarction volume ranges from 1.64—350.35 mL. We divided the infarction volume into three groups: low, medium and high volume. Plasma fibrinogen levels ranges from 88.3 mg/dl to 723.4 mg/dl. The lowest and highest fibrinogen levels were found in low volume group. The highest mean value of fibrinogen levels (362.0 mg / dl) was in medium volume group, while the lowest (310.4 mg/dL) was in low volume group. Cerebral infarction volume through non-contrast head MSCT scan varied from 1.64 mL to 350.35 mL. Fibrinogen levels in acute ischemic stroke patients varied from 88.3 mg/dL to 723.4 mg / dL.

Keywords

  • ischemic stroke; non-contrast head CT scan; fibrinogen
  • References

    Aman AM, Soewondo P, Soelistijo SA, et al. Pedoman Pengelolaan Dislipidemia di Indonesia 2019. PB PERKENI. Jakarta; 2019

    American College of Cardiology. AHA 2019 Heart Disease and Stroke Statistics [homepage on the Internet]. c2019 [updated 2019 Feb 19; cited 2020 Aug 11]. Available from https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2019/02/15/14/39/aha-2019-heart-disease-and-stroke-statistics

    Azam R, Khan M, Arshed A. Correlation between mean plasma fibrinogen level and mean lesion volume on CT scan in acute ischemic stroke. Pakistan J. Med. Heal. Sci. 2015;9:1338–1341.

    Catanese L, Tarsia J, Fisher M. Acute ischemic stroke therapy overview. Circulation research. 2017;120(3):541-558.

    Chuang SY, Bai CH, Chen WH, Lien LM, Pan WH. Fibrinogen independently predicts the development of ischemic stroke in a Taiwanese population: CVDFACTS study. Stroke. 2009;40(5):1578-1584.

    Health Ministry of Indonesia. Hasil Utama Riskesdas 2018 [homepage on the Internet]. c2018 [updated 2018 Nov 11; cited 2020 Aug 10]. Available from https://www.kemkes.go.id/resources/download/info-terkini/hasil-riskesdas-2018.pdf

    Johnson W, Onuma O, Owolabi M, Sachdev S. Stroke: a global response is needed. Bull. World Health Organ. 2016;94;634A-635A.  https://doi.org/10.2471/BLT.16.181636

    Khandait V, Barai P. Study of fibrinogen levels in patients of acute stroke. Int. J. Res. Med. Sci. 2018;7:20. https://doi.org/10.18203/2320-6012.ijrms20185356

    Lukito AA, Harmeiwaty E, Hustrini NM. Konsensus Penatalaksanan Hipertensi 2019. Perhimpunan Dokter Hipertensi Indonesia. Jakarta; 2019

    Ng JL, Chan MT, Gelb AW. Perioperative stroke in noncardiac, nonneurosurgical surgery. Anesthesiology: The Journal of the American Society of Anesthesiologists. 2011;115(4):879-890.

    Packard RRS, Libby P. Inflammation in atherosclerosis: From vascular biology to biomarker discovery and risk prediction. Clin. Chem. 2008;54:24–38. https://doi.org/10.1373/clinchem.2007.097360

    Ritarwan K, Yenita Y. Nilai prognostik parameter fibrinogen dan uji reliabilitas terhadap outcome stroke iskemik akut. Buletin Farmatera. 2017;2(2):56-66.

    Soelistijo SA, Novida H, Rudijanto A, et al. Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia 2015. PB. PERKENI. Jakarta; 2015