The study aimed at investigating the macro economic impact of Covid-19 in Uganda. The study adopted exploratory research design and 100 respondents participated. Primary data was collected using questionnaires and secondary data was obtained from government websites, International Agencies? websites, and other authentic online sources. Data was analyzed using SPSS v25. Study findings indicate that Covid-19 will wreak havoc on macroeconomic factors like inflation, unemployment and poverty. The study concluded that the government of Uganda should brace for the looming economic recession. We recommend that, Ugandan government should not be reluctant in investing heavily in the economic and health infrastructures owing to the fact that Covic-19 and other future pandemics will affect millions of Ugandans if it is not nipped in the bud. The study further recommends that government should direct central bank to reduce on interest rates as one of the means of rejuvenating the apparently dying economy.